Frequently Asked Questions About Garli-Eze’s™ Unique Allicin Delivery System
Which May Help Maintain a Healthy Cardiovascular System
Q: What is Garli-Eze?
A: Garli-Eze is a new, proprietary all natural diet supplement which delivers high levels of biologically active allicin, as high as levels obtained by eating fresh garlic, to the upper gastrointestinal track for absorption without producing any adverse side effect such as stomach upset, the so-called “garlic burp".
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Q: What is allicin?
A: Allicin is a very short-lived bioactive sulfur compound in garlic. Since 1993 a number of peer-reviewed and published studies have demonstrated an association between allicin standardized garlic supplement consumption and antimicrobial, antibacterial, blood thinning, lipid reduction and other cardiovascular benefits.¹
The nutritional composition of allicin requires elegant and sophisticated methods to ensure its delivery to the gastrointestinal track (GI) and very advanced analytical methods to measure its appearance.
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Q: Why is the level of allicin delivered to the GI so critical?
A: Consumption of garlic supplements with standardized allicin levels as part of a healthy diet and active lifestyle may help maintain a healthy cardiovascular system.
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Q: What makes Garli-Eze different from other garlic products?
A: Using innovative state-of-the-art manufacturing we have developed a process that delivers as much natural allicin as fresh garlic to the GI track without any adverse health effects. This new, all natural proprietary process is designed to eliminate the usual acidic reaction, the so-called ‘garlic burp,’ when high potency garlic mixes with stomach acid.
In fact, Garli-Eze activates in stomach acid yet doesn’t use an ‘enteric coating’, which typically employs a mix of synthetic chemicals designed to protect the capsule contents from stomach acid. Garli-Eze is the first commercial garlic product to perform like fresh, raw garlic.
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Q: Why is this study important?
A: The study presented used a method developed by Dr. Larry Lawson, a world renowned garlic researcher, and which was published as a seminal research article in 2005 in the Journal of Agricultural and Food Chemistry. This method employs a highly sensitive method of analyzing the breath after ingestion of garlic and unequivocally can determine if garlic was both delivered to the body for absorption, and its subsequent absorption.
It is important to note that this study is the first to independently confirm the ability of a garlic supplement to provide the activity of fresh, raw garlic yet is easy on the stomach and the breath. Using the Lawson method, this preliminary human study indicates that Garli-Eze can deliver large amounts of allicin directly to the upper gastrointestinal tract where it can be easily absorbed without the usual stomach upset.
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Q: Is eating raw garlic associated with any adverse side effects?
A: Yes. Eating raw garlic can cause stomach upset, offensive odors and other adverse side effects.
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Q: What does the scientific literature demonstrate about allicin consumption and cardiovascular health?
A: A number of peer-reviewed and published studies have demonstrated an association between allicin consumption and antimicrobial, antibacterial, blood thinning, lipid reduction and other cardiovascular benefits. Dr. Lawson notes, “Of all the effects of garlic that have been reported over the years, perhaps the most interesting on those on the heart and circulatory system.”²
A July 2005 peer-reviewed and published review article concluded, “Garlic has long been used medicinally, most recently for its cardiovascular, antineoplastic, and antimicrobial properties. Sulfur compounds, including allicin, appear to be the active components in the root bulb of the garlic plant. Studies show significant but modest lipid-lowering effects and antiplatelet activity.³
In a 1999 randomized, double-blind, placebo-controlled clinical trial, the plaque volumes in both carotid and femoral arteries of 152 probationers were determined by B-mode ultrasound. Continuous intake of high-dose garlic powder reduced significantly the increase in atherosclerotic plaque volume by 5–18% or even effected a slight regression within the observational period of 48 months. Also the age-dependent representation of the plaque volume shows an increase between 50 and 80 years that is diminished under garlic treatment by 6–13% related to 4 years. It seems even more important that with garlic application the plaque volume in the whole collective remained practically constant within the age-span of 50–80 years. These results substantiated that not only a preventive but possibly also a curative role in arteriosclerosis therapy (plaque regression) may be ascribed to garlic remedies.4
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Q: What is the history of garlic use in folk medicine?
A: Garlic, the so-called “spice of life” is well documented in promoting good health and is recorded in the earliest known medical writings, such as Papyrus Ebers scroll.5 Indeed, Indian manuscripts dating from 500 AD treat garlic almost as a panacea for all known ills.6 Later, in 1843 the German physician Georg Friedrich Most, published what at the time was considered a popular family health book which attributed various medicinal properties to the consumption of garlic relating to: ear and tooth aches, herpes, stomach trouble, mucous cough, a remedy for blushing and many other ills.7 By the end of World War II the scientific community has recognized garlic’s properties as a carminative for dyspeptic issues, as an antimicrobial for bacterial and fungal infections. Most recently researchers have studied and published reports on garlic’s ability to help maintain a healthy cardiovascular system.8
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Q: Who is NPI?
A: NPI is Nutra Products, Inc.), an innovative northern California-based company focused on the innovation of science driven bioactives for out-licensing to consumer health products marketers. Garli-Eze is its first intellectual property ready for commercialization.
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Disclaimer: These statements have not been evaluated by the FDA. This product is not intended to diagnose, treat, cure or prevent any disease.
- Rahman K and Lowe G, Garlic and Cardiovascular Disease: A Critical Review, J. Nutr. 136: 736S-740S, 2006.
- Koch H, Lawson S., Garlic: The Science and Therapeutic Application of Allium sativum L. and Related Species, 1996, p. 135.
- Tattelman E, Health Effects of Garlic, American Family Physican, Vol. 72, Number 1, (July 2005), 103-106.
- Koscielny J, Klu¨ßendorf D, Latza R, Schmitt R, Radtke H, Siegel G, Kiesewetter H, The antiatherosclerotic effect of Allium sativum, Atherosclerosis 144 (1999) 237–249.
- Koch H, Lawson S., p. v.
- Weiss, R.F. (1983) Arjuveda-Medizin and Phytotherapie. Z. Phytother. 4:615-620.
- Most, G.F. (1843) Encyklopadie der gesamten Volsmedicin oder Lexikon der vorzuglichstein und wirksamsten Haus- und Volksarzneimittel aller Lander. Brockhaus, Leipzig.
- Koch, Lawson, 135.
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